Publikationen 2006
Publikationen 2007
Publikationen 2008
Publikationen 2009
Publikationen 2010
Publikationen 2011
Publikationen 2012
Publikationen 2013
Publikationen 2014
Publikationen 2015
Publikationen 2016
Publikationen 2017
Publikationen 2018
Publikationen 2019



363 L.F. Tietze, F. Major Synthesis of New Water-Soluble DNA-Binding Subunits for Analogues of the Cytotoxic Antibiotic CC-1065 and Their Prodrugs. Eur. J. Org. Chem. 2006, 2314-2321. Online
364 L.F. Tietze, G. Brasche, C. Stadler, A. Grube, N. Böhnke Multiple Palladium-Catalyzed Reactions for the Synthesis of Analogues of the Highly Potent Insecticide Spinosyn A. Angew. Chem. 2006, 118, 5137-5140; Angew. Chem., Int. Ed. 2006, 45, 5015-5018. Online
365 L.F. Tietze, T. Kinzel, S. Schmatz Origin of Syn/Anti Diastereoselectivity in Aldehyde and Ketone Crotylation Reactions: A Combined Theoretical and Experimental Study. J. Am. Chem. Soc. 2006, 128, 11483-11495. Online
366 L.F. Tietze, B. Krewer, H. Frauendorf, F. Major, I. Schuberth Investigation of Reactivity and Selectivity of DNA-Alkylating Duocarmycin Analogues by High-Resolution Mass Spectrometry. Angew. Chem. 2006, 118, 6720-6724; Angew. Chem., Int. Ed. 2006, 45, 6570-6574. Online
367 L.F. Tietze, F. Major, I. Schuberth Antitumor Agents: Development of Highly Potent Glycosidic Duocarmycin Analogues for Selective Cancer Therapy. Angew. Chem. 2006, 118, 6724-6727; Angew. Chem., Int. Ed. 2006, 45, 6574-6577. Online
368 L.F. Tietze, F. Lotz Pd-Catalysed Domino Arylation/CH Activation for the Synthesis of Acenaphthylenes. Eur. J. Org. Chem. 2006, 4676-4684. Online
369 L.F. Tietze F. Stecker, J. Zinngrebe, K. M. Sommer Enantioselective Palladium-Catalyzed Total Synthesis of Vitamin E by Employing a Domino Wacker-Heck Reaction. Chem. Eur. J. 2006, 12, 8770-8776. Online
370 L.F. Tietze K. M. Gericke, R. R. Singidi Enantioselective Total Synthesis and Structure Determination of the Antiherpetic Anthrapyran Antibiotic AH-1763 IIa. Angew. Chem. 2006, 118, 7146-7150; Angew. Chem., Int. Ed. 2006, 45, 6990-6993. Online
371 L.F. Tietze, K. M. Gericke, C. Güntner First Total Synthesis of the Bioactive Anthraquinone Kwanzoquinone C and Related Natural Products by a Diels-Alder Approach. Eur. J. Org. Chem. 2006, 4910-4915. Online
372 L.F. Tietze, R.R. Singidi, K.M. Gericke First Enantioselective Total Synthesis and Structure Determination of the Anthrapyran Metabolite g-Indomycinone. Org. Lett. 2006, 8, 5873-5876. Online
373 L.F. Tietze, K.F. Wilckens, S. Yilmaz, F. Stecker, J. Zinngrebe Synthesis of 2,3-Dihydrobenzo[1,4]dioxins and -oxazins via a Domino Wacker-Heck Reaction. Heterocycles 2006, 70, 309-319. Online
374 L.F. Tietze, F. Lotz Asymmetric Heck and other Palladium Catalysed Reactions in "Asymmetric Synthesis - The Essentials"(Eds.: Christmann, Bräse) Wiley-VCH, Weinheim, 2006, p. 147-152.


375 L.F. Tietze, N. Böhnke, G. Brasche Preparation of (2R)-2-acetoxy-D-forosamine for the total synthesis of spinosyns. Arkivoc 2007, 12-21. Online
376 L.F. Tietze, C. Stadler, N. Böhnke, G. Brasche, A. Grube Synthesis of Enantiomerically Pure Cyclopentene Building Blocks. Synlett 2007, 485-487. Online
377 L.F. Tietze, K.M. Gericke, R.R. Singidi, I. Schuberth Novel strategies for the synthesis of anthrapyran antibiotics: discovery of a new antitumor agent and total synthesis of (S)-espicufolin. Org. Biomol. Chem. 2007, 5, 1191-1200. Online
378 L.F. Tietze, T. Kinzel Synthesis of natural products and analogs using multiple Pd-catalyzed transformations. Pure Appl. Chem. 2007, 79, 629-650. Online
379 L.F. Tietze, F. Major, I. Schuberth, D.A. Spiegl, B. Krewer, K. Maksimenka, G. Bringmann, J. Magull Selective Treatment of Cancer: Synthesis, Biological Evaluation and Structural Elucidation of Novel Analogues of the Antibiotic CC-1065 and the Duocarmycins. Chem. Eur. J. 2007, 13, 4396-4409. Online
380 L.F. Tietze, H. Braun, P.L. Steck, S.A.A. El Bialy, N. Tölle, A. Düfert Efficient synthesis of cephalotaxine- and deoxyharringtonine analogues by a trimethylaluminium-mediated domino reaction. Tetrahedron 2007, 6437-6445. Online
381 L.F. Tietze, G. Brasche, A. Grube, N. Böhnke, C. Stadler Synthesis of Novel Spinosyn A Analogues by Pd-Mediated Transformations. Chem. Eur. J. 2007, 13, 8543-8563. Online
382 L.F. Tietze, K. M. Gericke, I. Schuberth Synthesis of Highly Functionalized Anthraquinones and Evaluation of Their Antitumor Activity. Eur. J. Org. Chem. 2007, 4563-4577. Online
383 L.F. Tietze, R.R. Singidi, K.M. Gericke Total Synthesis of the Proposed Structure of the Anthrapyran Metabolite δ-Indomycinone. Chem. Eur. J. 2007, 13, 9939-9947. Online
384 L.F. Tietze, R.R. Singidi, K.M. Gericke, H. Böckemeier, H. Laatsch Isolation, Enantioselective Total Synthesis and Structure Determination of the Anthrapyran Metabolite. Eur. J. Org. Chem. 2007, 5875-5878. Online
385 L.F. Tietze, J. Zinngrebe, D.A. Spiegl, F. Stecker Palladium-catalyzed Domino-Wacker-Carbonylation Reaction for the Enantioselective Synthesis of Chromans and Benzodioxins. Heterocycles 2007, 74, 473-489. Online


386 L.F. Tietze, C. Raith, C.C. Brazel, S. Hölsken, J. Magull Enantioselective Synthesis of 2-Substituted Alcohols Using (+)-(1S,2S)-Pseudoephedrine as Chiral Auxiliary. Synthesis 2008, 229-236. Online
387 L.F. Tietze, H.J. Schuster, S.M. Hampel, S. Rühl, R. Pfoh Enantio- and Diastereoselective Synthesis of Duocarmycine-Based Prodrugs for a Selective Treatment of Cancer by Epoxide Opening Chem. Eur. J. 2008, 14, 895-901. Online
388 L.F. Tietze, I. Krimmelbein Enantioselective Total Synthesis of the Oral Contraceptive Desogestrel via a Double Heck Reaction. Chem. Eur. J. 2008, 14, 1541-1551. Online
389 L.F. Tietze, N. Tölle, C. Noll Highly Efficient Domino Reaction for the Synthesis of the Erythrina and B-Homoerythrina Alkaloid Skeleton. Synlett 2008, 525-528. Online
390 L.F. Tietze, T. Redert, H.P. Bell, S. Hellkamp, L.M. Levy Efficient Synthesis of the Structural Core of Tetracyclines by a Palladium-Catalyzed Domino Tsuji-Trost-Heck-Mizoroki Reaction. Chem. Eur. J. 2008, 14, 2527-2535. Online
391 L.F. Tietze, O. Panknin, F. Major, B. Krewer Synthesis of a Novel Pentagastrin-Drug Conjugate for a Targeted Tumor Therapy. Chem. Eur. J. 2008, 14, 2811-2818. Online
392 L.F. Tietze, T. Kinzel, S. Schmatz Determination of the Origin of Stereoselectivity in Multiple-Transition-State Reactions Using DFT Calculations: Enantioselective Synthesis of Homoallylic Alcohols from Aliphatic Methyl Ketones via an Auxiliary-Mediated Allylation. J. Am. Chem. Soc. 2008, 130, 4386-4395. Online
393 L.F. Tietze, C.A. Vock, I.K. Krimmelbein, J.M. Wiegand, L. Nacke, T. Ramachandar, K.M.D. Islam, C. Gatz Synthesis of Novel Structurally Simplified Estrogen Analogues. Chem. Eur. J. 2008, 14, 3670-3679. Online
394 L.F. Tietze, D. Liu Continuous-flow microreactor multi-step synthesis of an aminonaphthalene derivative as starting material for the preparation of novel anticancer agents. Arkivoc 2008, 193-210. Online
395 I. Elghamry, L.F. Tietze Microwave assisted synthesis of novel annealed porphyrins. Tetrahedron Lett. 2008, 49, 3972-3975. Online
396 L.F. Tietze, O. Panknin, B. Krewer, F. Major, I. Schuberth Synthesis and Biological Evaluation of a Novel Pentagastrin-Toxin Conjugate Designed for a Targeted Prodrug Monotherapy of Cancer. Int. J. Mol. Sci. 2008, 9, 821-837. Online
397 L.F. Tietze, C.C. Brazel, S. Hölsken, J. Magull, A. Ringe Total Synthesis of Polyoxygenated Cembrenes. Angew. Chem. 2008, 120, 5324-5327; Angew. Chem., Int. Ed. 2008, 47, 5246-5249. Online
398 L.F. Tietze, H.J. Schuster, K. Schmuck, I. Schuberth, F. Alves Duocarmycin based Prodrugs for Cancer Prodrug-Monotherapy. Bioorg. Med. Chem. 2008, 16, 6312-6318. Online
399 D.B. Werz, H. Schuster, L.F. Tietze Fast and Efficient Preparation of an α-Fucosyl Building Block by Reductive 1,2-Benzylidene Ring Opening Reaction. Synlett 2008, 1969-1972. Online
400 L.F. Tietze, D.A. Spiegl, F. Stecker, J. Major, C. Raith, C. Grosse Stereoselective Synthesis of 4-Dehydroxydiversonol Employing Enantioselective Palladium-Catalysed Domino Reactions. Chem. Eur. J. 2008, 14, 8956-8963. Online
401 L.F. Tietze, J.M. von Hof, B. Krewer, M. Müller, F. Major, H.J. Schuster, I. Schuberth Asymmetric Synthesis and Biological Evaluation of New Glycosidic Prodrugs for a Selective Cancer Therapy. ChemMedChem 2008, 3, 1946-1955. Online


402 L.F. Tietze, T. Kinzel, S. Schmatz Stereoselective Allylation of Ketones: Explanation for the Unusual Inversion of the Induced Stereochemistry in the Auxiliary-Mediated Crotylation and Pentylation of Butanone by DFT Calculations. Chem. Eur. J. 2009, 15, 1706-1712. Online
403 K.M.D. Islam, M. Dilcher, C. Thurow, C. Vock, I.K. Krimmelbein, L.F. Tietze, V. Gonzalez, H. Zhao, C. Gatz Directed evolution of estrogen receptor proteins with altered ligand-binding specificities. PEDS 2009, 22, 45-52. Online
404 L.F. Tietze, H.J. Schuster, B. Krewer, I. Schuberth Synthesis and Biological Studies of Different Duocarmycin based Glycosidic Prodrugs for their use in Antibody-Directed Enzyme Prodrug Therapy. J. Med. Chem. 2009, 52, 537-543. Online
405 L.F. Tietze, L. Levy The Mizoroki-Heck Reaction in Domino Processes in "The Mizoroki-Heck Reaction" (Ed.: M. Oestreich) Wiley-VCH, Chichester, 2009, p. 281-344.
406 L.F. Tietze, T. Kinzel, C. Brazel The Domino Multicomponent Allylation Reaction for the Stereoselective Synthesis of Homoallylic Alcohols. Acc. Chem. Res. 2009, 42, 367-378. Online
407 L.F. Tietze, B. Krewer Novel Analogues of CC-1065 and the Duocarmycins for the Use in Targeted Tumour Therapies. Anti-Cancer Agents Med. Chem. 2009, 9, 304-325. Online
408 L.F. Tietze, A. Heins, M. Soleiman-Beigi, C. Raith Synthesis of Annulated 1,4-Dioxanes and Perhydro-1,4-oxazines by Domino-Wacker-Carbonylation and Domino-Wacker-Mizoroki-Heck Reactions. Heterocycles 2009, 77, 1123-1146. Online
409 C. Dullin, M. Zientkowska, J. Napp, J. Missbach-Guentner, H.-W. Krell, F. Müller, E. Grabbe, L.F. Tietze, F. Alves Semi-automatic landmark-based 2D-3D image fusion in living mice: Correlation of near-infrared fluorescence imaging of Cy5.5 labeled antibodies with flat-panel volume computed tomography. Molecular Imaging 2009, 8, 1-14. Online
410 L.F. Tietze, D.A. Spiegl, C.C. Brazel Domino Reactions for the Efficient Synthesis of Natural Products in "Experiments in Green and Sustainable Chemistry" (Ed.: H.W. Roesky, D.K. Kennepohl) Wiley-VCH, Weinheim, 2009, p. 158-167.
411 F. Alves, C. Dullin, J. Napp, J. Missbach-Guentner, K. Jannasch, J. Mathejczyk, L.A. Pardo, W. Stühmer, L.F. Tietze Concept of a selective tumour therapy and its evaluation by near-infrared fluorescence imaging and flat-panel volume computed tomography in mice. Eur. J. Radiol. 2009, 70, 286-293. Online
412 L.F. Tietze, T. Kinzel, T. Wolfram Asymmetric Allylation of Methyl Ketones Using Chiral Phenyl Carbinols. Chem. Eur. J. 2009, 15, 6199-6210. Online
413 L.F. Tietze, C.A. Vock, I.K. Krimmelbein, L. Nacke Synthesis of Novel Structurally Simplified Estrogen Analogues with Electron-Donating Groups in Ring A. Synthesis 2009, 2040-2060. Online
414 L.F. Tietze, N. Böhnke, S. Dietz Synthesis of the Deoxyaminosugar(+)-D-Forosamine via a Novel Domino-Knoevenagel-Hetero-Diels-Alder Reaction. Org. Lett. 2009, 11, 2948-2950. Online
415 L.F. Tietze, B. Krewer, H. Frauendorf Investigation of the transformations of a novel anti-cancer agent combining HPLC, HPLC-MS and direct ESI-HRMS analyses. Anal. Bioanal. Chem. 2009, 437-448. Online
416 L.F. Tietze, B. Krewer Antibody-Directed Enzyme Prodrug Therapy: A Promising Approach for a Selective Treatment of Cancer Based on Prodrugs and Monoclonal Antibodies. Chem. Biol. Drug Des. 2009, 74, 205-211. Online
417 L.F. Tietze, B. Krewer, F. Major, I. Schuberth CD-spectroscopy as a powerful tool for investigating the mode of action of unmodified drugs in live cells. J. Am. Chem. Soc. 2009, 131, 13031-13036. Online
418 L.F. Tietze, B. Krewer, H. Frauendorf Probing the mechanism of action of potential anticancer agents at a molecular level using electrospray ionisation Fourier transform ion cyclotron resonance mass spectrometry. Eur. J. Mass Spectrom. 2009, 15, 661-672. Online
419 L.F. Tietze, B. Krewer, J.M. von Hof, H. Frauendorf, I. Schuberth Determination of the Biological Activity and Structure Activity Relationships of Drugs Based on the Highly Cytotoxic Duocarmycins and CC-1065. Toxins 2009, 1, 134-150. Online
420 L.F. Tietze, N. Tölle, D. Kratzert, D. Stalke Efficient Formal Total Synthesis of the Erythrina Alkaloid (+)-Erysotramidine Using a Domino Process. Org. Lett. 2009, 11, 5230-5233. Online
421 L.F. Tietze, A. Düfert, F. Lotz, L. Sölter, K. Oum, T. Lenzer, T. Beck, R. Herbst-Irmer Synthesis of Chiroptical Molecular Switches by Pd-Catalyzed Domino Reactions. J. Am. Chem. Soc. 2009, 131, 17879-17884. Online
422 S.A. Opiyo, J.A. Ogur, L.O.A. Manguro, L.F. Tietze, H. Schuster A new sterol diglycoside from Conyza floribunda. S. Afr. J. Chem. 2009, 62, 163-167. Online


423 L.L. Bajohr, L. Ma, C. Platte, O. Liesenfeld, L.F. Tietze, U. Groß, W. Bohne In-vitro and in-vivo activity of 1-hydroxy-2-alkyl-4(1H)quinolone derivatives against Toxoplasma gondii. Antimicrob. Agents Chemother. 2010, 54, 517-521. Online
424 M. Schubert, A.N. Melnikova, N. Mesecke, E.K. Zubkova, F. Fortte, D.R. Batashev, I. Barth, N. Sauer, Y.V. Gamalei, N.S. Mamushina, L.F. Tietze, O.V. Voitsekhovskaja, K. Pawlowski Two novel disaccharides, rutinose and methylrutinose, are involved in carbon metabolism in Datisca glomerata. Planta 2010, 231, 507-521. Online
425 H.J. Schuster, B. Krewer, J.M. von Hof, K. Schmuck, I. Schuberth, F. Alves, L.F. Tietze Synthesis of the first spacer containing prodrug of a duocarmycin analogue and determination of its biological activity. Org. Biomol. Chem. 2010, 8, 1833-1842. Online
426 L.F. Tietze, A. Düfert Multiple Pd-catalyzed reactions in the synthesis of natural products, drugs, and materials. Pure Appl. Chem. 2010, 82, 1375-1392. Online
427 L.F. Tietze, A. Düfert Domino Reactions Involving Catalytic Enantioselective Conjugate Additions in "Catalytic Asymmetric Conjugate Reactions" (Ed.: A. Cordova) Wiley-VCH, Weinheim, 2010, p. 321-350.
428 L.F. Tietze, S. Biller, T. Wolfram First Enantioselective Total Synthesis of the Reported Structure of (R)-(+)-Orizaterpenyl Benzoate Using an Asymmetric Allylation of a Prochiral Ketone in a Domino Process. Synlett 2010, 2130-2132. Online
429 L.F. Tietze, J.M. von Hof, M. Müller, B. Krewer, I. Schuberth Glycosidic Prodrugs of Highly Potent Bifunctional Duocarmycin Derivatives for Selective Treatment of Cancer. Angew. Chem. 2010, 122, 7494-7497. Angew. Chem., Int. Ed. 2010, 49, 7336-7339. Online
430 L.F. Tietze, H.J. Schuster, J.M. von Hof, S.M. Hampel, J.F. Colunga, M. John Atropisomerism of Aromatic Carbamates. Chem. Eur. J. 2010, 16, 12678-12682. Online
431 L.F. Tietze, F. Behrendt, F. Major, B. Krewer, J.M. von Hof Synthesis of Fluorescence Labeled Glycosidic Prodrugs Based on the Cytotoxic Antibiotic Duocarmycin. Eur. J. Org. Chem. 2010, 6909-6921. Online
432 L.F. Tietze, L. Ma Synthesis of Novel 1-Hydroxyquinolones with High Anti-Toxoplasma Activity. Heterocycles 2010, 82, 377-396. Online


433 L.F. Tietze, K. Schmuck, H.J. Schuster, M. Müller, I. Schuberth Synthesis and Biological Evaluation of Prodrugs Based on the Natural Antibiotic Duocarmycin for Use in ADEPT and PMT. Chem. Eur. J. 2011, 17, 1922-1929. Online
434 C.M. Seubert, J. Stritzker, U. Donat, J.B. Sturm, N. Chen, J.M. von Hof, B. Krewer, L.F. Tietze, I. Gentschev, A.A. Szalay Enhanced tumor therapy using vaccinia virus strain GLV-1h68 in combination with a β-galactosidase-activatable prodrug seco-analog of duocarmycin SA. Cancer Gene Ther. 2011, 18, 42-52. Online
435 L.O.A. Manguro, J.O. Midiwo, L.F. Tietze, P. Hao Triterpene saponins of Maesa lanceolata leaves. Arkivoc 2011, 172-198. Online
436 L.F. Tietze, M.A. Düfert, T. Hungerland, K. Oum, T. Lenzer Synthesis and Photochemical Investigations of Tetrasubstituted Alkenes as Molecular Switches-The Effect of Substituents. Chem. Eur. J. 2011, 17, 8452-8461. Online
437 L.F. Tietze, K. Schmuck SiFa Azide - A New Building Block for PET Imaging Using Click Chemistry. Synlett 2011, 1697-1700. Online
438 L.F. Tietze, S. Dietz, N. Böhnke, M. A. Düfert, I. Objartel, D. Stalke Three-Component Domino Knoevenagel/Hetero-Diels-Alder Reaction for the Synthesis of the Amino Sugars 2-Acetoxyforosamine and 2-Acetoxyossamine - Experimental and Theoretical Results. Eur. J. Org. Chem. 2011, 6574-6580. Online
439 L.F. Tietze, K. Schmuck Prodrugs for Targeted Tumor Therapies: Recent Developments in ADEPT, GDEPT and PMT. Curr. Pharm. Des. 2011, 17, 3527-3547. Online
440 J.E. Mathejczyk, J. Pauli, C. Dullin, J. Napp, L.F. Tietze, H. Kessler, U. Resch-Genger, F. Alves Spectroscopically Well-Characterized RGD Optical Probe as a Prerequisite for Lifetime-Gated Tumor Imaging. Molecular Imaging 2011, 10, 469-480. Online


441 L.A. Pardo, D. Gomez-Varela, F. Major, K. Sansuk, R. Leurs, B.R. Downie, L.F. Tietze, W. Stühmer Approaches Targeting KV10.1 Open a Novel Window for Cancer Diagnosis and Therapy. Curr. Med. Chem. 2012, 19, 675-682. Online
442 J.E. Rixson, T. Chaloner, C.H. Heath, L.F. Tietze, S.G. Stewart The Development of Domino Reactions Incorporating the Heck Reaction: The Formation of N-Heterocycles. Eur. J. Org. Chem. 2011, 544-558. Online
443 L.F. Tietze, T. Hungerland, M.A. Düfert, I. Objartel, D. Stalke Synthesis of tetra-substituted Alkenes through a Pd-catalyzed domino-Carbopalladation/CH-Activation. Chem. Eur. J. 2012, 18, 3286-3291. Online
444 T. Wirth, K. Schmuck, L.F. Tietze, S.A. Sieber Duocarmycin analogues target aldehyde dehydrogenase 1 in lung cancer cells. Angew. Chem. 2012, 124, 2928-2931; Angew. Chem., Int. Ed. 2012, 51, 2874-2877. Online
445 L.F. Tietze, T. Wolfram, J.J. Holstein, B. Dittrich First Enantioselective Total Synthesis of (+)-(R)-Pinnatolide Using an Asymmetric Domino Allylation Reaction. Org. Lett. 2012, 14, 4035-4037. Online
446 L.F. Tietze, T. Hungerland, C. Depken, C.Maaß, D. Stalke Palladium-catalyzed Domino-Carbopalladation/CH-Activation for the Synthesis of Tetrasubstituted Alkenes bearing 5- and 7-membered Rings. Synlett 2012, 2516-2520. Online
447 L.F. Tietze, N. Schützenmeister, A. Grube, T. Scheffer, M. M. Baag, M. Granitzka, D. Stalke Synthesis of Novel Spinosyn Analogues for Modern Crop Protection. Eur. J. Org. Chem. 2012, 5748-5756. Online
448 T. Iven, S. König, S. Singh, S.A. Braus-Stromeyer, M. Bischoff, L.F. Tietze, G.H. Braus, V. Lipka, I. Feussner, Wolfgang Dröge-Laser Transcriptional Activation and Production of Tryptophan-Derived Secondary Metabolites in Arabidopsis Roots Contributes to the Defense against the Fungal Vascular Pathogen Verticillium longisporum. Mol. Plant, 2012, 5, 1389-1402. Online
449 L.F. Tietze, M.A. Düfert, S.-C. Schild General Principles of Diastereoselective Reactions: Diastereoselective Domino Reactions. In: Carreira E.M. and Yamamoto H. (eds.) Comprehensive Chirality, 2012, Volume 2, pp. 97-121. Amsterdam: Elsevier.
450 L.F. Tietze, F. Behrendt, G.F. Pestel, I. Schuberth, M. Mitkovski Synthesis, Biological Evaluation and Live Cell Imaging of Novel Fluorescent Duocarmycin Analogues. Chem. Biodiversity 2012, 2559-2570. Online
451 L.F. Tietze, A. Heins, J.R. Reiner, S.-C. Duefert, I. Schuberth Synthesis and Biological Evaluation of a Novel Acronycine/Duocarmycin Hybrid Natural Product. Heterocycles 2012, 425-433. Online
452 L.F. Tietze, S.G. Stewart, A. Düfert Domino Reactions in the Enantioselective Synthesis of Bioactive Natural Products in "Modern Tools for the Synthesis of Complex Bioactive Molecules" (Ed.: J. Cossy, S. Arseniyadis) John Wiley & Sons, 2012, p. 271-334 (ISBN-13: 978-0470616185).


453 L.F. Tietze, M. Müller, S.-C. Duefert, K. Schmuck, I. Schuberth Photoactivatable Prodrugs of Highly Potent Duocarmycin Analogues for a Selective Cancer Therapy. Chem. Eur. J. 2013, 19, 1726-1731. Online
454 L.F. Tietze, S.-C. Duefert, J. Clerc, M. Bischoff, C. Maaß, D. Stalke Total Synthesis of Linoxepin through a Palladium-Catalyzed Domino Reaction. Angew. Chem. 2013, 125, 3273-3276; Angew. Chem., Int. Ed. 2013, 52, 3191-3194. Online
455 L.F. Tietze, T. Hungerland, C. Eichhorst, A. Düfert, C. Maaß, D. Stalke Efficient Synthesis of Helical Tetrasubstituted Alkenes as Potential Molecular Switches: A Two-Component Palladium-Catalyzed Triple Domino Process. Angew. Chem. 2013, 125, 3756-3759; Angew. Chem., Int. Ed. 2013, 52, 3668-3671. Online
456 L.F. Tietze, S. Jackenkroll, C. Raith, D.A. Spiegl, J.R. Reiner, M.C. Ochoa Campos Enantioselective Total Synthesis of (-)-Diversonol. Chem. Eur. J. 2013, 19, 4876-4882. Online
457 L.F. Tietze, S.A. Sieber Duocarmycin Analogues without a DNA-Binding Indole Unit Associate with Aldehyde Dehydrogenase 1A1 and not DNA: A Reply. Angew. Chem. 2013, 125, 5557-5559; Angew. Chem., Int. Ed. 2013, 52, 5447-5449. Online
458 L.F. Tietze, L. Ma, J.R. Reiner, S. Jackenkroll, S. Heidemann Enantioselective Total Synthesis of (-)-Blennolide A. Chem. Eur. J. 2013, 19, 8610-8614. Online
459 T. Wirth, G.F. Pestel, V. Ganal, T. Kirmeier, I. Schuberth, T. Rein, L.F. Tietze, S.A. Sieber The Two Faces of Potent Antitumor Duocarmycin-Based Drugs: A Structural Dissection Reveals Disparate Motifs for DNA versus Aldehyde Dehydrogenase 1 Affinity. Angew. Chem. 2013, 125, 7059-7063; Angew. Chem., Int. Ed. 2013, 52, 6921-6925. Online
460 L.F. Tietze, S. Dietz, N. Schützenmeister, S. Biller, J. Hierold, T. Scheffer, M.M. Baag Selective Glycosylation with the Amino Sugar D-Forosamine for the Synthesis of Spinosyns and Its Analogues. Eur. J. Org. Chem. 2013, 7305-7312. Online
461 L.F. Tietze, T. Hungerland, J. Ammermann, C. Eichhorst, S.O. Reichmann, D. Stalke A facile synthesis of 3-substituted benzofurans and indoles through a palladium-catalyzed domino carbopalladation/CH-activation/isomerization process. Ind. Chem. Soc. 2013, 90, 1537-1555.
462 K.-C. Chen, K. Schmuck, L.F. Tietze, S.R. Roffler Selective Cancer Therapy by Extracellular Activation of a Highly Potent Glycosidic Duocarmycin Analogue. Mol. Pharmaceutics 2013, 10, 1773-1782. Online


463 L.F. Tietze, L. Ma, S. Jackenkroll, J.R. Reiner, J. Hierold, B. Gnanaprakasam, S. Heidemann The Paecilin Puzzle - Enantioselective Synthesis of the Proposed Structures of Paecilin A and B. Heterocycles 2014, 88, 1101-1119. Online
464 L.F. Tietze, S.-C. Düfert, J. Hierold Domino Reactions in the Total Synthesis of Natural Products in "Domino Reactions: Concepts for Efficient Organic Synthesis" (Ed.: L.F. Tietze) Wiley-VCH, Weinheim, 2014, p. 523-578.
465 L.F. Tietze, S. Jackenkroll, J. Hierold, L. Ma, B. Waldecker A Domino Approach to the Enantioselective Total Syntheses of Blennolide C and Gonytolide C. Chem. Eur. J. 2014, 20, 8628-8635. Online
466 L.F. Tietze, C. Eichhorst, T. Hungerland, M. Steinert A Fast Way to Fluorescence: A Fourfold Domino Reaction to Condensed Polycyclic Compounds. Chem. Eur. J. 2014, 20, 12553-12558. Online
467 L.F. Tietze, J. Clerc, S. Biller, S.-C. Duefert, M. Bischoff Enantioselective Total Synthesis of the Lignan (+)-Linoxepin. Chem. Eur. J. 2014, 20, 17119–17124. Online


468 L.F. Tietze, C. Eichhorst An efficient Domino Sonogashira/double Carbopalladation/C-H-Activation Reaction leading to Fluorescent Polycyclic Aromatic Hydrocarbons. Heterocycles 2015, 90, 919-927. Online
469 L.F. Tietze, T. Eicher, U. Diederichsen, A. Speicher, N. Schützenmeister Reactions and Syntheses in the Organic Chemistry Laboratory, 2nd Edition (completely revised and updated), Wiley-VCH, Weinheim, 2015.
470 L.F. Tietze, B. Waldecker, D. Ganapathy, C. Eichhorst, T. Lenzer, K. Oum, S.O. Reichmann, D. Stalke Four-and Sixfold Tandem-Domino Reactions Leading to Dimeric Tetrasubstituted Alkenes Suitable as Molecular Switches. Angew. Chem. 2015, 127, 10457-10461; Angew. Chem., Int. Ed. 2015, 54, 10317-10321. Online
471 M.F. Koch, S. Harteis, I.D. Blank, G. Pestel, L.F. Tietze, C. Ochsenfeld, S. Schneider and S.A. Sieber Structural, Biochemical, and Computational Studies Reveal the Mechanism of SelectiveAldehydeDehydrogenase 1A1 Inhibitionby Cytotoxic Duocarmycin Analogues. Angew. Chem. 2015, 127, 13754-13758; Angew. Chem., Int. Ed. 2015, 54, 13550-13554. Online
472 J. Hierold, S. Baek, R. Rieger, T.-G. Lim, S. Zakpur, M. Arciniega, K.W. Lee, R. Huber, L.F. Tietze Design, Synthesis, and Biological Evaluation of Quercetagetin Analogues as JNK1 Inhibitors. Chem. Eur. J. 2015, 21, 16887-16894. Online
473 D. Ganapathy, J.R. Reiner, L.E. Löffler, L. Ma, B. Gnanaprakasam, B. Niepötter, I. Koehne, L.F. Tietze Enantioselective Total Synthesis of Secalonic Acid E. Chem. Eur. J. 2015, 21, 16807-16810. Online


474 L.F. Tietze, S. Jackenkroll, D. Ganapathy, J.R. Reiner Formal Synthesis of (-)-Siccanin Using an Enantioselective Domino Wacker/Carbonylation/Methoxylation Reaction. Synlett 2016, 27, 96-100. Online
475 J. Napp, L.A. Pardo, F. Hartung, L.F. Tietze, W. Stühmer, F. Alves In vivo imaging of tumour xenografts with an antibody targeting the potassium channel Kv 10.1. Eur. Biophys. J. 2016, 45, 721-733. Online


476 D. Ganapathy, J.R. Reiner, G. Valdomir,S. Senthilkumar, L.F. Tietze Enantioselective Total Synthesis and Structure Confirmation of the Natural Dimeric Tetrahydroxanthenone Dicerandrol C. Chem. Eur. J. 2017, 23, 2299-2302.
477 L.F.Tietze, M. Bischoff, T.A. Khan, D. Liu Synthesis of indolizinoquinolinones through three- and four-component domino Knoevenagel / hetero-Diels–Alder reactions: novel access to (+)-camptothecin. Chem. Heterocycl. Comp. 2017, 53, 434-445.
478 L.F.Tietze Obituary for Prof. Dr. Burchard Franck. Angew. Int. Ed. Engl. 2017, 56, 16445.


479 R. Gandamala, S. Hoekman, M. Kangani, J. E. Nidhiry, K. Penchalaiah, D. Singh, L. F. Tietze Synthesis and Biology of Dimeric, Trimeric and Tetrameric Analogues of Duocarmycin SA. Heterocycles 2018, 97, 260-272. Online
480 T. A. Khan, T. Fornefeld, D.Hübner, P. Vana, L. F. Tietze Palladium-Catalyzed Fourfold Domino Reaction for the Synthesis of a Polymeric Double Switch. , Org. Lett. 2018, 20, 2007-2010. Online
481 S. Senthilkumar, G. Valdomir , D. Ganapathy, Y. Zhang, L. F. Tietze Enantioselective Total Synthesis of the Fungal Metabolite Blennolide D and the Enantiomers of Blennolide E and F. , Org. Lett. 2018, 20, 2186-2189. Online
482 G. Valdomir, S. Senthilkumar, D. Ganapathy, Y. Zhang, L. F. Tietze Enantioselective Total Synthesis of Blennolide H and Phomopsis-H76 A and Determination of Their Structure , Chem. Eur. J. 2018, 24, 8760-8763. Online
483 G. Valdomir, S. Senthilkumar, D. Ganapathy, Y. Zhang, L. F. Tietze Enantioselective Total Synthesis of Chromanone Lactone Homo- and Heterodimers. , Chem. Asian J. 2018, 13, 1888-1891. Online
484 F. Lotz, K. Kahle, M. Kangani, S. Senthil Kumar, L. F. Tietze Domino C–H Activation Reactions through Proximity Effects. , Eur. J. Org. Chem. 2018, 5562-5569. Online


485 T. A. Khan, L. F. Tietze Synthesis of a Poly-Heterocyclic Tetra-substituted Alkene via a Palladium-Catalyzed Fourfold Domino Reaction for the Design of Polymeric Molecular Switches. Heterocycles 2019, prepress.
486 C. De Ford, K. Penchalaiah, A. Kreft, M. Humar, W. Heydenreuter, M. Kangani, S. A. Sieber, L. F. Tietze, I. Merfort Bifunctional Duocarmycin Analogues as Inhibitors of Protein Tyrosine Kinases. J. Nat. Prod. 2019, 82, 16-26. Online


Last Update 09. April 2018 . Please report any error to Martina Pretor